Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Tendon rupture
ADR ID BADD_A04248
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.07      Muscle, tendon and ligament injuries
12.01.07.003      Tendon rupture
15      Musculoskeletal and connective tissue disorders
15.07      Tendon, ligament and cartilage disorders
15.07.01      Tendon disorders
15.07.01.008      Tendon rupture
Description Not Available
MedDRA Code 10043248
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Achilles tendon rupture | Biceps tendon rupture | Nontraumatic rupture of achilles tendon | Nontraumatic rupture of extensor tendons of hand and wrist | Nontraumatic rupture of flexor tendons of hand and wrist | Nontraumatic rupture of other tendon | Nontraumatic rupture of other tendons of foot and ankle | Nontraumatic rupture of patellar tendon | Nontraumatic rupture of quadriceps tendon | Nontraumatic rupture of tendons of biceps (long head) | Nontraumatic rupture of unspecified tendon | Rupture Achiles tendon | Rupture of tendon, nontraumatic | Rupture tendon | Ruptured Achilles tendon | Tendon achilles rupture of | Tendon rupture | Tendon rupture NOS | Torn Achilles tendon (traumatic) | Non-traumatic rupture of achilles tendon | Non-traumatic rupture of patellar tendon | Non-traumatic rupture of quadriceps tendon | Non-traumatic rupture of unspecified tendon | Rupture of tendon, non-traumatic | Severed tendon | Quadriceps tendon rupture
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01014Gemifloxacin mesylate--
BADD_D01086Hydrocortisone0.000224%
BADD_D01089Hydrocortisone cypionate--
BADD_D01091Hydrocortisone sodium succinate--
BADD_D01119Ibrutinib0.001066%
BADD_D01243Lamotrigine--
BADD_D01252Leflunomide0.005164%
BADD_D01253Lenalidomide--
BADD_D01257Letrozole0.008613%
BADD_D01275Levofloxacin0.015514%
BADD_D01322Losartan0.000049%
BADD_D01325Lovastatin0.000179%
BADD_D01336Macitentan--
BADD_D01401Metformin--
BADD_D01418Methotrexate--
BADD_D01433Methylprednisolone0.000142%
BADD_D01434Methylprednisolone acetate--
BADD_D01435Methylprednisolone hemisuccinate--
BADD_D01436Methylprednisolone sodium succinate--
BADD_D01476Mirtazapine--
BADD_D01501Moxifloxacin0.000578%
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01567Nilotinib0.000799%
BADD_D01587Norfloxacin--
BADD_D01598Ofloxacin0.000796%
BADD_D01599Olanzapine0.002164%
BADD_D01645Oxycodone0.000093%
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01824Pravastatin0.000145%
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